Dr. Amy B. Killen MD

Dr. Amy B. Killen MD

Longevity Curve

Magic Mushrooms for Longevity?

And... My Personal Psychedelics Story

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Dr. Amy B. Killen MD
Dec 22, 2025
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Look, I know what you’re thinking. Dr. Amy B. Killen-It has finally lost it! She’s ditched her hormone evangelism for... checks notes... recommending we all start microdosing magic mushrooms for eternal youth?

Not quite. But buckle up, because the research I’m about to share is genuinely mind-bending, and I mean that both literally and figuratively.

The Study That Made Me Do a Double-Take

A few weeks ago, I attended the Longevity Global Summit at the Buck Institute, where a researcher (Dr. Louise Hecker) presented findings that made everyone in the room sit up straighter: monthly “hero doses” of psilocybin (the active compound in magic mushrooms) extended lifespan in aged mice. And as a bonus? It gave them better skin and hair.

The study, published in npj Aging (that’s a Nature Partner Journal, so we’re talking rigorous peer review, not some fringe publication), is the first experimental evidence that psilocybin might be a legitimate anti-aging intervention. This isn’t a hippie fever dream. This is serious science.

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